Phentermine 37.5mg – Powerful Appetite Suppressant for Weight Loss | Adipex-P® Equivalent
Phentermine 37.5mg is a prescription-strength appetite suppressant used for short-term weight loss in adults struggling with obesity. It is most effective when combined with a doctor-approved low-calorie diet, exercise, and behavioral changes. Phentermine is a sympathomimetic amine, chemically similar to amphetamines, and works by stimulating the central nervous system (CNS) to reduce hunger.
This high-dose formulation is commonly prescribed as a kick-start for weight loss, especially for individuals with a BMI over 30 or over 27 with obesity-related risk factors (e.g. high blood pressure, diabetes).
Chemical & Pharmacological Profile:
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Active Ingredient: Phentermine Hydrochloride
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Strength: 37.5mg
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Formula: C10H15N
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Drug Class: CNS stimulant / Anorectic agent
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Controlled Substance: Schedule IV (U.S. FDA)
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Mechanism of Action: Stimulates release of norepinephrine and dopamine to suppress appetite and increase metabolism
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Onset: ~1 hour
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Duration: ~12–14 hours
Common Brand Names:
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Adipex-P®
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Lomaira® (lower-dose version)
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Ionamin®
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Suprenza®
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Fastin® (U.S. only – reformulated)
🏷️ Generic Phentermine HCl 37.5mg tablets and capsules are also widely available.
Medical Uses:
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Short-term treatment of obesity
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For patients with:
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BMI ≥30
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Or BMI ≥27 with risk factors (hypertension, high cholesterol, insulin resistance)
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Often prescribed for 8–12 weeks alongside a weight loss plan
Dosage & Administration:
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Typical adult dose: 37.5mg once daily, taken in the morning
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Can also be split into 18.75mg twice daily
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Take before breakfast or 1–2 hours after, with water
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Avoid evening dosing due to insomnia risk
Warnings & Side Effects:
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Common: Dry mouth, insomnia, restlessness, increased heart rate, elevated blood pressure
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Serious: Chest pain, shortness of breath, mood changes, high blood pressure
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Not recommended for:
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Patients with cardiovascular disease, glaucoma, hyperthyroidism, or history of substance abuse
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Not for long-term use (>12 weeks)
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Pregnancy Category X – Do not use during pregnancy or breastfeeding
Shipping & Availability:
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Ships to USA, UK, and select international regions
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Available in capsule or tablet form
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Discreet shipping, bulk pricing, trusted generic brands

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