Oxycodone 60mg

Oxycodone 60mg – Extended & Immediate Release for Severe Chronic Pain Management

Oxycodone 60mg is a high-strength, semi-synthetic opioid analgesic prescribed for the management of moderate to severe chronic pain, especially in opioid-tolerant patients. Available in both Immediate-Release (IR) and Extended-Release (ER) versions, Oxycodone 60mg is designed to provide either quick relief or 12-hour continuous control of pain caused by injury, surgery, cancer, or nerve disorders.

This medication works by binding to mu-opioid receptors in the brain and central nervous system, blocking pain signals and altering the body’s perception of discomfort. Oxycodone 60mg is not intended for casual or first-time opioid users and should only be used under proper medical guidance.

It is sold under popular global brands like OxyContin®, Oxynorm®, Longtec®, and Roxicodone®, including Mundipharma-manufactured variants in the UK and EU.

Chemical & Pharmacological Overview:

• Active Ingredient: Oxycodone Hydrochloride

• Strength: 60mg per tablet

• Chemical Formula: C18H21NO4

• Drug Class: Opioid analgesic (Schedule II)

• Mechanism of Action: Binds to mu-opioid receptors → blocks pain transmission

• IR Onset: 20–30 minutes

• ER Onset: 45–60 minutes

• IR Duration: 4–6 hours

• ER Duration: Up to 12 hours

Brand Names (by Formulation):

Immediate-Release (IR) Brands – 60mg:

• Oxynorm® IR (UK – Mundipharma)

• Roxicodone® IR (US – Mallinckrodt, Caraco)

• OxyIR® (US generics)

Used for breakthrough or fast-onset pain management in opioid-tolerant users.

Extended-Release (ER) Brands – 60mg:

• OxyContin® ER (US – Purdue Pharma | UK – Mundipharma)

• Longtec® (UK generic ER oxycodone)

• Xtampza ER® (US – Collegium)

• Reltebon® (UK ER)

• Targin® (ER with naloxone) – Mundipharma

Designed for long-lasting control of chronic pain with reduced risk of breakthrough symptoms.

Indications (Medical Uses):

• Severe chronic pain (e.g. cancer, spinal conditions, arthritis)

• Palliative and hospice care

• Neuropathic and musculoskeletal pain

• Major post-surgical recovery

• Long-term opioid therapy rotation

Dosage & Administration Guidelines:

• ER: 60mg tablet every 12 hours (do not split or crush)

• IR: 60mg total per day divided into 3–4 doses (e.g., 15–20mg every 4–6 hours)

• Caution: For use only in opioid-experienced patients

• Swallow tablets whole with water

• Never mix with alcohol or other CNS depressants

Warnings & Side Effects:

• Risk of addiction, abuse, and overdose

• Schedule II controlled substance (U.S.)

• May cause respiratory depression, dizziness, nausea, constipation, dry mouth, or confusion

• Not for use in pregnancy or with other sedatives

• Tolerance and physical dependence can develop quickly

Shipping & Availability:

• Ships to all U.S. states and United Kingdom regions

• Prescription-optional availability in select jurisdictions

• Discreet packaging – no medication name on box

• Fast processing within 24–48 hours

• Tracked and insured delivery