Oxycodone 20mg

Oxycodone 20mg – Fast-Acting & Extended Pain Relief | IR & ER Options

Oxycodone 20mg is a powerful semi-synthetic opioid analgesic designed for the management of moderate to severe pain, particularly in patients who need consistent and long-term opioid therapy. Available in both Immediate-Release (IR) and Extended-Release (ER) formats, it ensures pain relief with fast onset or around-the-clock control.

It works by activating mu-opioid receptors in the central nervous system, altering pain perception and response. This formulation is suitable for opioid-tolerant patients and should be prescribed with caution due to its potency and risk of misuse.

Major brand names include Endocodil® IR 20mg, Oxynorm®, OxyContin®, Longtec®, and Xtampza ER®.

Chemical & Pharmacological Profile:

• Active Ingredient: Oxycodone Hydrochloride

• Strength: 20mg per tablet

• Chemical Formula: C18H21NO4

• Drug Class: Opioid analgesic (Schedule II controlled substance, US DEA)

• Mechanism: Mu-opioid receptor agonist

• IR Onset: 15–30 minutes

• ER Onset: ~45–60 minutes

• IR Duration: 4–6 hours

• ER Duration: 10–12 hours

Brand Names by Formulation:

Immediate-Release (IR):

• Endocodil® IR 20mg (Europe/UK – Endo Pharmaceuticals)

• Oxynorm® IR (UK – Mundipharma)

• Roxicodone® IR (USA)

• OxyIR® (US generics)

Best suited for breakthrough pain, fast relief after injury or surgery.

Extended-Release (ER):

• OxyContin® ER (USA – Purdue Pharma / UK – Mundipharma)

• Longtec® (UK – Teva & generics)

• Xtampza ER® (USA – Collegium)

• Targin® ER (Oxycodone + Naloxone combo)

• Reltebon® ER

Used for consistent, long-term pain control — especially in cancer care or neuropathic pain.

Medical Indications:

• Cancer-related pain management

• Arthritis or nerve damage

• Lower back, joint, or spinal pain

• Post-surgical pain

• Severe dental or orthopedic injuries

• Palliative care

Dosage & Use:

 Recommended for opioid-tolerant adults only

• IR Tablets (e.g., Endocodil 20mg): 1 tablet every 4–6 hours as needed

• ER Tablets (e.g., OxyContin 20mg): 1 tablet every 12 hours (do not split/crush)

• Always take with water

• Avoid alcohol, sedatives, or CNS depressants during use

• Dosage must be personalized by a licensed professional

Side Effects & Warnings:

• May cause drowsiness, euphoria, dizziness, nausea, dry mouth, or constipation

• High risk of addiction, respiratory depression, and overdose

• Not for use in pregnancy or patients with respiratory disorders

• Schedule II drug – misuse may lead to criminal liability

• Avoid operating machinery while under medication effect

Shipping & Purchase Details:

• Discreet packaging – no drug names on label

• Ships to all U.S. states and major UK cities

• Optional no-prescription purchase in certain zones

• Shipping time: 2–5 business days

• Tracked delivery and secure payment support