Oxycodone 80mg

Oxycodone 80mg – Extended & Immediate Release | High-Potency Opioid Pain Relief

Oxycodone 80mg is a powerful semi-synthetic opioid analgesic used for the management of severe and chronic pain that does not respond to non-opioid alternatives. It comes in both Immediate-Release (IR) and Extended-Release (ER) forms to offer flexible pain control options, depending on the medical condition and patient need.

This medication works by binding to mu-opioid receptors in the brain and spinal cord, significantly lowering the body’s perception of pain and increasing tolerance to long-lasting or acute discomfort. With long-standing use in oncology, orthopedic injuries, trauma care, and post-operative pain, Oxycodone 80mg is not intended for opioid-naïve patients and should be used only under medical supervision.

Now available online (with or without prescription) and shipped discreetly across the USA and UK.

Pharmacological Overview:

• Active Ingredient: Oxycodone Hydrochloride

• Strength: 80mg per tablet

• Chemical Formula: C18H21NO4

• Drug Class: Opioid (semi-synthetic narcotic analgesic)

• Mechanism of Action: Mu-opioid receptor agonist

• Onset (IR): 15–30 minutes

• Onset (ER): 60 minutes

• Duration (IR): 4–6 hours

• Duration (ER): 10–12 hours

Common Brand Names by Release Type:

Immediate-Release (IR) – 80mg:

• Roxicodone® IR (USA – Mallinckrodt, Caraco)

• Oxynorm® IR (UK – Napp/Mundipharma)

• Endone® (Australia)

• OxyIR® (U.S. generics)

Used for breakthrough pain and rapid onset relief in patients already on opioid therapy.

Extended-Release (ER) – 80mg:

• OxyContin® ER (USA – Purdue Pharma, UK – Mundipharma)

• Xtampza ER® (USA – Collegium Pharma)

• Targin® ER (UK – Mundipharma, with naloxone)

• Longtec® (UK generic ER oxycodone)

• Reltebon® (UK ER version)

Designed for 12-hour round-the-clock relief in chronic pain conditions like cancer or severe musculoskeletal pain.

Indications (Medical Uses):

• Cancer-related pain

• End-of-life/palliative care

• Severe musculoskeletal pain

• Post-surgical pain management

• Severe arthritis or neuropathy

• Spinal injuries or trauma pain

• Opioid Rotation (for tolerant patients)

Dosage & Administration:

⚠ For opioid-tolerant patients only.

• IR Use: 80mg split into smaller doses (e.g., 20–40mg) every 4–6 hours as needed

• ER Use: One 80mg tablet every 12 hours (do not crush/chew)

• Always swallow whole. Breaking or crushing can lead to fatal overdose.

• Avoid alcohol and CNS depressants

Warnings & Side Effects:

• Controlled Substance – Schedule II (USA)

• May cause respiratory depression, nausea, constipation, dizziness, euphoria, or confusion

• Risk of addiction, misuse, and overdose

• Not suitable for pregnant women

• Do not drive or operate heavy machinery

Shipping & Availability:

• Ships across the United States and United Kingdom

• Discreet, sealed packaging

• No medication names on the parcel

• Fast 24–48 hour dispatch with tracking